Efficacy of tranexamic acid in reducing blood loss during lower segment caesarean section

Tranexamic acid in decreasing blood loss during and after caesarean section.

OBJECTIVE To determine the effectiveness of tranexamic acid (TXA) in reducing blood loss during and after caesarean section (CS), as well as its safety. STUDY DESIGN A randomized double-blind placebo controlled study. PLACE AND DURATION OF STUDY The Lyari General Hospital, Karachi, from March 2009 till April 2011. METHODOLOGY Women undergoing lower segment caesarean section (LSCS) were en...

Minimizing Blood Loss during Lower Segment Cæsarean Section

The efficacy of tranexamic acid in reducing blood loss in total shoulder arthroplasty

BACKGROUND The purpose of this meta-analysis is to compare the efficacy of tranexamic acid (TXA) versus placebo after a total shoulder arthroplasty (TSA). METHODS In April 2017, a systematic computer-based search was conducted in the databases of PubMed, Embase, Web of Science, Cochrane Library, and Google. Studies comparing TXA versus placebo in reducing blood loss after TSA were included. T...

Estimation of blood loss during Caesarean section: an audit.

OBJECTIVE To evaluate the blood ordering practice and blood transfusion for Caesarean sections at our institution and to compare the estimated blood loss between anaesthetists and obstetricians. METHODS A review of 126 patients undergoing both elective and emergency Caesarean section was undertaken in 2002. Information collected included the number of blood units cross-matched preoperatively,...

Use of Tranexamic Acid (TXA) on reducing blood loss during scoliosis surgery in Chinese adolescents

BACKGROUND Many reports had been received on the application of antifibrinolytic medications on spinal corrective surgery and the surgical outcome evaluations of its efficacy on reducing blood loss. This study aimed to assess the efficacy of tranexamic acid (TXA) in reducing operative blood loss during posterior spinal fusion for the treatment of severe adolescent idiopathic scoliosis (AIS). ...